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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '147ca19e794a6443cb9d4ff781bd9c783295bd61b6ea6d62690192d67dda16dd' 
  AND token = 'Y0tYER0W8yTnOQGEWTMsnMeHR4O9ILJYRyI4cNzthYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}