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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a54bca9f049ee8c030e6d4772b6b2fce88e409ccc63896482f393ae9d28875e' 
  AND token = '0+Mkt7LRD1lpR3dttYfgDsK2rOW3wIIg+LTtbYVjJ48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}