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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '915d258bc2acb6f8ae6de8829c206e47a76ac365dfc577becc697a705dd20d01' 
  AND token = 'B2hzSpcIiM/OMbyst6CN3vs5m8wV/5F1W26zd445KVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}