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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05a0bb445c8b18bf0d5f189533dc44362a20eef5fe993dab0ef4d8c0c25c7b73' 
  AND token = 'TQKxqCEEsFxL+PwMsNcoFfuZc8z04cjY43sz/1vS3AA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}