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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfe22e119d4ac28d182ec0b3486445bb08112d791462dd41aced7dbcb07a8821' 
  AND token = 'A72K2NAdKJtZUdm0JDZCgxd4hZE04AQqX+C8Fp0iDdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}