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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e2d9e15355c153e90ff21641d93bb8b976d6c4eaf9a5063947959eb59fef6e4' 
  AND token = 'EtrBfs6r2IKlE+Mu/jHztzWGdSACWzBHgfsEV5sU7dY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}