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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f43ab589d98cac99afc10cf0d58ee6b05b79d531c3b851dfd1eb89c62e7b39f' 
  AND token = '33OPwWX+k4P8OieCAfS18KLTLF0zJ9AAYOjyFqQxQZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}