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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4df9ae38212bda82e7ce27d120ed1d76962bcbce8d5a7117e0500448a86e92f8' 
  AND token = '+vWP3Or1Ya7QBlSHak9AEzNV6YWebOVjaLTK5MJqtQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}