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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '197a52e4facc506e93fb23614df277be599ca99b7897363f2ed9bada26ee85ec' 
  AND token = 'HrmGeTdCDzBlZ7ZqO2UDEOxK3TpMeup0Duxm6vt4GVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}