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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fa7456875a01b2f5b8b3b4b22f6d8ff5aa48d7d1edc5cffa4c205367e0f02aa' 
  AND token = 'Ltd72PNLH4XzMWSHH0eDnHIOT2SdDKqYael1v/tEsmA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}