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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03f0e6f71f0fbce0a090cd2343672a52110eef3f6ade3d1da646f22b05f8fb3f' 
  AND token = 'Wq3RwbzYtD9X7+VyfNpUx9FhkT77xtg6qFAjL8s4tRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}