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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '449b0fbb3f64cf7997f631487a34d2781a73bd0cf9b721b336ee7c8485ebca00' 
  AND token = '8txHN/BQ5oZTcBcMTdIzeiejoLE0NrX3IVuTjLj167U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}