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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '865a87bdf59a24708b81c3792cf0460a4b0ece526f33eb12e3c962e357f623f0' 
  AND token = 'waDYWCtd9bs6lS+SIx9ZaBWzb3Z5e8GlkHpc5Ob/wUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}