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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5aa3d0252f23b106165fcfa8d61a83e410850114b33f98fb958f7685d6182c15' 
  AND token = 'i0iJV+RxE6E0Tsxdkus8Fdt7MsbRp8p1zM42iVRXZmc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}