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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f66078860461ba27452b41fca89bd86d655f8fb6f1cfd36e6bf8553d8bf13da4' 
  AND token = 'wfKii7sAhhOa9hftapitw5j7wX/9H7EQtMIJnSIWNqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}