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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1530d71d12848da42a2311d2bef99fa6acdb9490bc6439d40bdc33995fe55a32' 
  AND token = '7ZNO6BDdz3eZ7wgdIeeOaclzBhjSwbxoc6TrIIgL2O0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}