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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bc8b97ea544fbbdbcfc16c7053b5efd2be8bb83ee367bd4282b20d93aa625fc' 
  AND token = 'K2HYt0cUzLgVK//8M++P6bsx75rwZpD3gd9vNVRWEwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}