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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e3e35f272fe0bd634c48857b84988fdc75824e54aec23d2a944f7b5e92b8cf3' 
  AND token = '4NjPiXGFffFI0OMDLSN7JDyWUW4hlTgsUM0Xr+9K4eQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}