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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f15366cf6ebbda6597e4701e6d4fa54e7e4b60340ff3e57768d3b16705a10a47' 
  AND token = 'PMNxKXHQ+Hja+4bUzujzo8paMqMre69edJ2bSwqAdPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}