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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80e0ccc5738fc4638d9b5a5ae0cc25f0a8a56ac979025bd417954b6bc7486d1e' 
  AND token = 'AdMqSz6xKd9+KDiFuX6vlpg0XuR8EV2wjNgnTymR7PE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}