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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4561468fc647336b017a4560a113c72f95b779f628a3a2872ea01f1b8877a7e2' 
  AND token = '0cZX4LtwWnW1otpLc+iFMH/Pb86WLamZduOt1uYzoEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}