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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1231f0400a088e2c99cb2876fc280ce02ea3a97cde1f3663ea409928b58bb279' 
  AND token = 'JWkxNqSDb/WhyUfdbqB930+Gp4OzRnGtYFdczO29Al4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}