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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c6df4babc6c95d7c4ac45c6344418dc2b7bb669e2c129c0d766d3a603343321' 
  AND token = '5NHusU2z4WfDxyg1fzgkj0Xr/kfymjZmUtRTyL3wtBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}