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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ef61fd7cac44eee7b256dbc3498f09f56a21fa225ec38dbc804dca3cd74adbb' 
  AND token = '7UflshUmihqxyiAAza7pgkTvDCMUwXmeJAGwRda9Z5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}