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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77a07e34fbc1fe97ee1e3fabb37c64ee389690deca030516cac7e16dca1a15b8' 
  AND token = 'GkOg9KI9MjPZR1bDlmIorYr+p96VIROXcPSzZoI7Tj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}