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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c8b31bbd2b91d98348e5a12b5528481664c472d15edd3d268d1ca529ca93068' 
  AND token = 'QjYM7kjAB+kBfEWPrTSqP0EUO7+PLwUFU6NYS+thwA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}