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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44ea8e71d4caa2133a847346735bd469fba6e32ebbcfe7c6f8287c4bb18d5e66' 
  AND token = 'nl/gYt+licJdkI+g7LpOCma2Kv5fRLRMmSPyqDNATHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}