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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e947ab4a61d3787d1c82e74b963e90b95a33a119838bbce8b0fc2771e1e73186' 
  AND token = 'F4N9j9M+WeREoddcrMxyuH4zCYrVOAZ9bZi8ZtlH2lc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}