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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a226bf830c9f8195329ce8cad45266b0b87eb6ab041f1f7864d0dea11b258c92' 
  AND token = '3EWZXVhcr3GAoLP9GaVtAVWyijfP80BYd3x1eFoWUgU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}