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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81821a887996d136e4c71c2c783e0fe475a0e3fcd927c7713af6e2d4aecb2c74' 
  AND token = 'zWg/YxuIWqL/qV/9B4YftDBVCFMCyCV2nmWvYNI5qb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}