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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8ba80e577d0283808f05c9eeaa3e1212bee53803276b85dfb16d840f6467bc5' 
  AND token = 'spWpyGvIQauxB1w+SFxiUjAdm5zXV9nxCet7zoEbBZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}