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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc717ff03c67d7cc3bfc1e2969b6bd6384758edeff1cedac4b97d44ff7f4dece' 
  AND token = 'QtiDed2fGrVMIQwaZY6cWmr2uxeIbG2ThUd7mAQT7p0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}