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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73823481e9499fa1c546a77237cf14b1c4611070d0079410d750c631d2635c86' 
  AND token = 'Flwmo897CxT/XwfZ+bEZn2p0O85AqEtNdh8hh9eUHIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}