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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7eae72b67317e6d4a99c88d0f1333f5fe706401ca54078c63db2da3c8d0b9388' 
  AND token = 'U/KL51TVCXk5gm+75+Pp1n4auUNG4b8NYqMRmHKCUiU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}