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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76355d5d6816f597bb9a7f6112706f9e62b60c57e7451373168012ae867b5702' 
  AND token = 'wqERSh5Rzas6CDyGUFigpnV6GYhWox73B47HXRr8ur0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}