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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e74d51811ab00029c69fa4379eb7b1f8d0d82a6c6506b99c44e3309d292fe47' 
  AND token = '1TILlbKP35mtUMfQp4enxwf83UpVN9ptYM9GY2ZhsY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}