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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1defdc7ef5269985f898a1ebd55adc2fdca549aaaf61512b4464052b4dc38edf' 
  AND token = 'y/9BdBmwsc+boIFajag5TZmflJ87otUKShxi2JmSZGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}