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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d577d4c72499bce368d7e0b2fd1295a9d5a1ff236d06d2225b8581c8ef0c4e6' 
  AND token = 'og+iLN3NKsCCaClz/FbEHP5VDdA1Br3+5HlnPIYDVR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}