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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d8a17422d9bf6dc06bf641f8d842dbc63f018b1b3f9d056eb0f0fd26a81fb48' 
  AND token = 'CtYDIFuzd0C/C5+G7Wf8sUpir9bJNbETTfPan4BLZHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}