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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d8444b921d155ee00968a46fe85f67b79d8486c7e858ee1d9080cdb18fcef7c' 
  AND token = '1E1xK95YvvCY+8RtxyAJFOtDiXZ7Az37KNmDJ+wMUoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}