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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ffe0b3a5142e995d8cc512a861f5a2a6b165677b2c5494a20dad8337bc022d1' 
  AND token = 'W5LpRBaaXzHdAnA3cisRvp7srXFYCh+FtRDghFktgAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}