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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ad7ec169a3d7bc53f1379e0375766fa2cfb75474ea3a0246861a9022b0159e9' 
  AND token = 'vvzX8T0dktf59Oe9K+6bzWSp3LA8PpiZkFLc64lUz2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}