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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ed92dcac9c1ce72b5800cf1b1751f636b2dc2d24978e28e7caf8161163ac823' 
  AND token = 'rNqesPH+YPcguPSsM4U1jMOQRqoZ6vOtoS6hWRJwZBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}