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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9de09009adfc66ba8cda941289bc81a7e0e03229e86dde685a914482aac03a8' 
  AND token = 'RL2lwgqDYg//Mc+nN3LIluQN9sMDzOUE2/7Md8NgWYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}