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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce98c98f265b634cdcdd65379dd55f678e37e257bb4a233c3fffc561c63c1166' 
  AND token = '+I9AHLkTA4D9KjxhITUhD0xlS+Hg7GKTEcj3t+hO/Zg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}