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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd1280947e48a5252ff1010e16e58705944ea1abe7928ca15af021db42d161f3' 
  AND token = 'CmYVexVGN6D291t7tmpUUjYc7zjWs3pu4/SKIr70IAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}