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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ad5b643196ee455d7ce81fab402e67bc1aced2b3fdd79f1d4ec45424cb86c89' 
  AND token = 'i2Ijagcux4/JVPPcyjnlqcLG6Onkr9lWeOUjthMlJ/w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}