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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5526cdc2749a6bab693b4e2078471415fb26a80ef66a998c0e0b719e273c1620' 
  AND token = 'JigeVeUXVCbY15clFTk6CfBsZXhxUQbIAe1wpJLFc84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}