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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4411149066dde7b93779e594b026a7cb550964a84d96156322ab14db51f59765' 
  AND token = 'YOxuyxtqjJU1zQuYxhWU8qTE7lnU5U7M8wk8x3AiuMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}