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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11681f2241d1b98322656288e980aa9bc33e99a57b7d2a82f7d44a1079f75978' 
  AND token = 'A6K8bYE5BQwTBb/40kC1VCEQwGMI1wCCdZYJcatU5Mc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}